van de Laar M J, van Duynhoven Y T, Fennema J S, Ossewaarde J M, van den Brule A J, van Doornum G J, Coutinho R A, van den Hoek J A
National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
Genitourin Med. 1996 Aug;72(4):261-5.
To study the association of serovars of Chlamydia trachomatis with clinical manifestations of genital tract infection and socio-demographic characteristics.
In 1986-88 the C trachomatis isolates from 159 heterosexual men and 116 women attending a sexually transmitted disease (STD) clinic were collected and typed accordingly. A medical history was recorded, a physical examination took place and samples were taken for laboratory diagnostics.
Serovars E, F and D were the most common for both men (75%) and women (67%). Men infected with serovars of the C-complex had more often a history of STD (p = 0.06). The opposite was demonstrated in women (p = 0.07). In addition, women younger than 18 years at first intercourse were more often infected with C-complex serovars (p = 0.05). For men, the serovars F/G less often produced symptoms of urethral discharge (p = 0.01) than the serovars of the B-complex and C-complex and were less often associated with the presence of 10 or more leukocytes in a Gram-stained smear (p = 0.04).
In this study, infections with serovars F and G caused less obvious symptoms and signs of inflammation in men; in women no differences were found in the clinical manifestation of infections with different serovars.
研究沙眼衣原体血清型与生殖道感染临床表现及社会人口学特征之间的关联。
1986年至1988年，收集了159名到性传播疾病（STD）门诊就诊的异性恋男性和116名女性的沙眼衣原体分离株，并进行相应分型。记录病史，进行体格检查，并采集样本进行实验室诊断。
血清型E、F和D在男性（75%）和女性（67%）中最为常见。感染C复合群血清型的男性患性传播疾病的病史更为常见（p = 0.06）。女性情况则相反（p = 0.07）。此外，首次性交时年龄小于18岁的女性感染C复合群血清型的情况更为常见（p = 0.05）。对于男性，血清型F/G产生尿道分泌物症状的情况比B复合群和C复合群血清型少见（p = 0.01），并且在革兰氏染色涂片中白细胞数量为10个或更多的情况也较少见（p = 0.04）。
在本研究中，血清型F和G感染在男性中引起的炎症症状和体征不太明显；在女性中，不同血清型感染的临床表现未发现差异。
