Is rifabutin prophylaxis against Mycobacterium avium complex infection in HIV infection worthwhile? The net impact on patients suggests not.
作者信息
Stephenson J M, Williams I G
机构信息
Department of Sexually Transmitted Diseases, University College, London Medical School, UK.
出版信息
Genitourin Med. 1996 Aug;72(4):272-6. doi: 10.1136/sti.72.4.272.
Abstract
摘要
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Is rifabutin prophylaxis against Mycobacterium avium complex infection in HIV infection worthwhile? The net impact on patients suggests not.利福布汀预防HIV感染患者鸟分枝杆菌复合群感染是否值得？对患者的总体影响表明不值得。
Genitourin Med. 1996 Aug;72(4):272-6. doi: 10.1136/sti.72.4.272.
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Recommendations on prophylaxis and therapy for disseminated Mycobacterium avium complex disease in patients infected with the human immunodeficiency virus. Public Health Service Task Force on Prophylaxis and Therapy for Mycobacterium avium Complex.人类免疫缺陷病毒感染患者播散性鸟分枝杆菌复合群病的预防和治疗建议。公共卫生服务鸟分枝杆菌复合群预防和治疗特别工作组。
N Engl J Med. 1993 Sep 16;329(12):898-904. doi: 10.1056/NEJM199309163291228.
2
Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group.医学文献用户指南。II. 如何使用关于治疗或预防的文章。B. 结果如何，它们对我照顾患者有帮助吗？循证医学工作组。
JAMA. 1994 Jan 5;271(1):59-63. doi: 10.1001/jama.271.1.59.
3
Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group.医学文献用户指南。II. 如何使用关于治疗或预防的文章。A. 研究结果是否有效？循证医学工作组。
JAMA. 1993 Dec 1;270(21):2598-601. doi: 10.1001/jama.270.21.2598.
4
Two controlled trials of rifabutin prophylaxis against Mycobacterium avium complex infection in AIDS.两项关于利福布汀预防艾滋病患者鸟分枝杆菌复合体感染的对照试验。
N Engl J Med. 1993 Sep 16;329(12):828-33. doi: 10.1056/NEJM199309163291202.
5
Bias in treatment assignment in controlled clinical trials.
N Engl J Med. 1983 Dec 1;309(22):1358-61. doi: 10.1056/NEJM198312013092204.
6
Confidence intervals rather than P values: estimation rather than hypothesis testing.置信区间而非P值：估计而非假设检验。
Br Med J (Clin Res Ed). 1986 Mar 15;292(6522):746-50. doi: 10.1136/bmj.292.6522.746.
7
In vivo activities of newer rifamycin analogs against Mycobacterium avium infection.新型利福霉素类似物对鸟分枝杆菌感染的体内活性。
Antimicrob Agents Chemother. 1991 Oct;35(10):2026-30. doi: 10.1128/AAC.35.10.2026.
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