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一名亚洲移民中的弥漫性泛细支气管炎

Diffuse panbronchiolitis in an Asian immigrant.

作者信息

Brugiere O, Milleron B, Antoine M, Carette M F, Philippe C, Mayaud C

机构信息

Department of Respiratory Medicine, Hôpital Tenon, Paris, France.

出版信息

Thorax. 1996 Oct;51(10):1065-7. doi: 10.1136/thx.51.10.1065.

Abstract

Diffuse panbronchiolitis (DPB) is a disease with chronic inflammation exclusively located in the region of the respiratory bronchiole. It is largely restricted geographically to the Far East, and cases in Western countries are exceptional, even among Asian immigrants. A patient of Asian origin with DPB who had been living in France for 10 years is described. Only re-examination of the initial open lung biopsy specimen after an eight year period allowed this rare disease to be diagnosed correctly. The known efficacy of low dose erythromycin in DPB was again confirmed after failure of long term high dose corticosteroid therapy administered before an accurate diagnosis had been made.

摘要

弥漫性泛细支气管炎(DPB)是一种慢性炎症仅局限于呼吸性细支气管区域的疾病。它在地理上主要局限于远东地区,西方国家的病例极为罕见,即使在亚洲移民中也是如此。本文描述了一名患有DPB的亚洲裔患者,他在法国生活了10年。仅在八年后对最初的开胸肺活检标本进行重新检查才得以正确诊断出这种罕见疾病。在准确诊断之前给予的长期高剂量皮质类固醇治疗失败后,低剂量红霉素在DPB中的已知疗效再次得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/472677/da120a65e1d4/thorax00329-0112-a.jpg

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