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针对假定风险群体的肺部及主观反应的环境臭氧实地研究。

Environmental ozone field study on pulmonary and subjective responses of assumed risk groups.

作者信息

Höppe P, Praml G, Rabe G, Lindner J, Fruhmann G, Kessel R

机构信息

Institute for Occupational and Environmental Medicine, Munich University, Germany.

出版信息

Environ Res. 1995 Nov;71(2):109-21. doi: 10.1006/enrs.1995.1072.

DOI:10.1006/enrs.1995.1072
PMID:8977619
Abstract

Lung function parameters (measured with a body plethysmograph) and subjective votes on irritations of eyes or airways were taken from subjects belonging to four assumed ozone risk groups and one control group (40 subjects each: senior citizens, juvenile asthmatics, forestry workers, athletes, and clerks). Every subject was examined on 8 days both in the morning and in the afternoon. The intention was to obtain an equal distribution of measuring days with elevated and low ozone concentrations, respectively, for each subject. On average the ozone concentrations reached 0.070 ppm on "ozone days" [maximum concentration 0.112 ppm for clerks (outdoors), 0.100 ppm for senior citizens, 0.091 for juvenile asthmatics, 0.086 ppm for athletes, and 0.077 ppm for forestry workers] and 0.028 ppm on "control days" (minimum 0.001 ppm). The results show no relevant ozone effect for the group with the lowest ventilation rate (senior citizens) and only marginal reductions of respiratory flows and volumes for athletes. Pulmonary decrements of juvenile asthmatics on ozone days were small but larger than those documented in the literature for healthy children. Forestry workers and clerks had significantly higher airway resistances on ozone days, although having been exposed to the lowest ozone concentrations of all groups. Thus, on days with moderately elevated levels of ozone in the environment it is assumed that ozone itself has a minor influence on pulmonary responses compared to that of other constituents of the air in certain locations like in forests or indoors on these days. These could be reaction products of ozone with motor tool exhausts in the case of forestry workers or substances originating from ozone deposition on the surfaces of the offices.

摘要

肺功能参数(用体描仪测量)以及关于眼睛或气道刺激的主观投票数据,取自四个假定的臭氧风险组和一个对照组的受试者(每组40人:老年人、青少年哮喘患者、林业工人、运动员和职员)。每位受试者在上午和下午各接受8天的检查。目的是让每位受试者在臭氧浓度高和低的测量日分别得到均等分布。在“臭氧日”,臭氧浓度平均达到0.070 ppm(职员在户外的最高浓度为0.112 ppm,老年人为0.100 ppm,青少年哮喘患者为0.091 ppm,运动员为0.086 ppm,林业工人为0.077 ppm),在“对照日”为0.028 ppm(最低为0.001 ppm)。结果显示,通气率最低的组(老年人)没有明显的臭氧效应,运动员的呼吸流量和容积仅有轻微下降。青少年哮喘患者在臭氧日的肺部功能下降虽小,但比文献中记载的健康儿童的下降幅度大。林业工人和职员在臭氧日的气道阻力显著更高,尽管他们接触的臭氧浓度在所有组中是最低的。因此,在环境中臭氧浓度适度升高的日子里,可以假定与某些场所(如森林或室内)空气中的其他成分相比,臭氧本身对肺部反应的影响较小。对于林业工人来说,这些成分可能是臭氧与电动工具废气的反应产物;对于职员来说,可能是源自臭氧在办公室表面沉积的物质。

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