Honnas C M, Cohen N D
Texas Veterinary Medical Center, Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843-4475, USA.
J Am Vet Med Assoc. 1997 Jan 1;210(1):78-81.
To determine the prevalence of wound infection following celiotomy in horses and to determine risk factors associated with the development of such infections.
Prospective study.
210 horses that had 235 celiotomies.
All horses that had celiotomies between March 1990 and March 1992 were considered for this study. Only horses that survived > or = 10 days after surgery were included in analysis of risk factors for postoperative wound infection.
Of the 210 horses, 161 (76.7%) were discharged; of the horses discharged, 147 horses had a single celiotomy and 14 had multiple celiotomies. Twenty-six (12.4%) horses were euthanatized during surgery and were, therefore, excluded from further analysis. Twenty-three horses died during the postoperative period. Of these 23 horses, 15 that died within 10 days of surgery also were excluded from further analysis. Thus, 169 horses were included in the analysis of risk factors for developing incisional infection. Evidence of incisional infection was observed in 43 of 169 (25.4%) horses. Increased concentration of fibrinogen in peritoneal fluid obtained prior to surgery, performing an enterotomy, and use of polyglactin 910 to close the linea alba were all significantly (P < or = 0.05) associated with increased risk of postoperative wound infection. Whether incisional herniation developed was recorded for 76 horses. The proportion of horses with hernias among those with postoperative wound infection was 19.1%, compared with 3.6% of horses without evidence of postoperative wound infection, indicating a significant association between postoperative wound infection and development of incisional hernias.
Increased concentration of fibrinogen in peritoneal fluid prior to surgery, performing an enterotomy, and use of polyglactin 910 to close the linea alba is significantly associated with increased risk for wound infection following celiotomy in horses.
确定马剖腹术后伤口感染的发生率，并确定与此类感染发生相关的风险因素。
前瞻性研究。
接受235次剖腹术的210匹马。
1990年3月至1992年3月间接受剖腹术的所有马匹均纳入本研究。仅将术后存活≥10天的马匹纳入术后伤口感染风险因素分析。
210匹马中，161匹（76.7%）出院；出院的马匹中，147匹接受了单次剖腹术，14匹接受了多次剖腹术。26匹（12.4%）马在手术期间实施安乐死，因此被排除在进一步分析之外。23匹马在术后死亡。在这23匹马中，15匹在术后10天内死亡，也被排除在进一步分析之外。因此，169匹马被纳入切口感染发生风险因素分析。169匹马中有43匹（25.4%）出现切口感染迹象。术前获得的腹腔液中纤维蛋白原浓度升高、进行肠切开术以及使用聚乙醇酸910闭合白线均与术后伤口感染风险增加显著相关（P≤0.05）。记录了76匹马是否发生切口疝。术后伤口感染的马匹中发生疝的比例为19.1%，而无术后伤口感染迹象的马匹中这一比例为3.6%，表明术后伤口感染与切口疝的发生之间存在显著关联。
术前腹腔液中纤维蛋白原浓度升高、进行肠切开术以及使用聚乙醇酸910闭合白线与马剖腹术后伤口感染风险增加显著相关。
