Chapoutot C, Perney P, Pageaux G P, Lefebvre A, Souche B, Blanc F
Service de Médecine Interne E, Hôpital Saint-Eloi, Montpellier.
Gastroenterol Clin Biol. 1996;20(8-9):700-2.
The incidence of listeriosis is increased in immunosuppressed patients. We report a case of spontaneous bacterial peritonitis with bacteraemia caused by Listeria monocytogenes in a 47-year old woman with liver transplantation. Complete recovery was achieved after amoxicillin and amikacin therapy. High doses of corticosteroids and OKT3 monoclonal therapy may have favoured the occurrence of infection. In liver transplant recipients, regular stool screening could be proposed, and trimethoprim-sulfamethoxazole antibioprophylaxy could be used when Listeria monocytogenes is isolated in stool culture or immunosuppressive therapy is increased.
李斯特菌病的发病率在免疫抑制患者中有所增加。我们报告了一例47岁肝移植女性患者发生由单核细胞增生李斯特菌引起的自发性细菌性腹膜炎并伴有菌血症的病例。阿莫西林和阿米卡星治疗后实现了完全康复。高剂量的皮质类固醇和OKT3单克隆治疗可能促使了感染的发生。对于肝移植受者，可建议进行定期粪便筛查，当粪便培养中分离出单核细胞增生李斯特菌或增加免疫抑制治疗时，可使用复方新诺明进行抗生素预防。
