Reinberg A E, Touitou Y
Unité de Chronobiologie, Foundation A. de Rothschild, Paris, France.
Pathol Biol (Paris). 1996 Jun;44(6):487-95.
Properties of biological rhythms are presented briefly as well as the conventional model dealing with the synchronizing effects of the day/night (or Light/Dark) alternation on the suprachiasmatic nuclei (SCN) the master-clock, which is supposed to control all our rhythms. However, apart from the SCN role, a set of experimental arguments supports the existence of biological clocks in the brain cortex. The synchronization of the latter (resetting them and making their period = 24 h) may be achieved not only by the periodicity of physical Light/Dark signals but also by the periodicity of social signals involving perceptions with eyes, ears, nose and skin. Distribution of peaks and troughs of biological rhythms in the 24h scale reveals the organism's temporal order. Its alteration (dyschronism) results from a phase shift and/or a change in the period length of a rhythm with regard to the others. In human beings, dyschronism is a trivial phenomenon. It appears even if synchronizers are present, with interindividual differences. It is likely that dyschronism induces a set of symptoms in sensitive subjects, prone to react to it.
本文简要介绍了生物节律的特性,以及传统模型中昼夜(或光/暗)交替对作为主时钟的视交叉上核(SCN)的同步作用,该主时钟被认为控制着我们所有的节律。然而,除了SCN的作用外,一系列实验证据支持大脑皮层中生物钟的存在。后者的同步(重置它们并使其周期 = 24小时)不仅可以通过物理光/暗信号的周期性来实现,还可以通过涉及眼睛、耳朵、鼻子和皮肤感知的社会信号的周期性来实现。生物节律在24小时尺度上的峰值和谷值分布揭示了生物体的时间顺序。其改变(节律失调)是由于相对于其他节律,节律的相位偏移和/或周期长度的变化所致。在人类中,节律失调是一种常见现象。即使存在同步器,个体之间也存在差异,它仍然会出现。在敏感个体中,节律失调很可能会引发一系列症状,他们容易对此做出反应。