通过聚合酶链反应（PCR）检测到牛性腺发育不全（XY雌性）中Y染色体上SRY区域的缺失。

Deletion of the SRY region on the Y chromosome detected in bovine gonadal hypoplasia (XY female) by PCR.

作者信息

Kawakura K, Miyake Y I, Murakami R K, Kondoh S, Hirata T I, Kaneda Y

机构信息

National Institute of Animal Industry, Tsukuba, Japan.

出版信息

Cytogenet Cell Genet. 1996;72(2-3):183-4. doi: 10.1159/000134182.

DOI:10.1159/000134182

PMID:8978769

Abstract

In 6 sterile heifers which were female in appearance and in genital organs, all tissues derived from blood, skin, spleen and kidney had a single 60,XY type of metaphase plate. Although the SRY gene was detected by PCR in normal bull, it was not detected in normal cow or in 3 60,XY cases studied.

摘要

在6头外表及生殖器官均为雌性的无菌小母牛中，所有来源于血液、皮肤、脾脏和肾脏的组织都有单一的60,XY型中期染色体板。虽然通过聚合酶链反应（PCR）在正常公牛中检测到了SRY基因，但在正常母牛或所研究的3例60,XY病例中均未检测到。