3号染色体区域3p21中多态性标记的排序
Ordering of polymorphic markers in the chromosome region 3p21.
作者信息
van den Berg A, Kooy R F, Hulsbeek M M, de Jong D, Kok K, van der Veen A Y, Buys C H
机构信息
Department of Medical Genetics, University of Groningen, The Netherlands.
出版信息
Cytogenet Cell Genet. 1996;72(2-3):225-8. doi: 10.1159/000134196.
Starting from five markers, with a well-defined order from distal to proximal 3p21, nine other markers could be inserted in this 3p21 map. Five were precisely mapped genetically. The other markers were ordered by FISH and/or deletion hybrid mapping. The overall 3p21 order from distal to proximal is as follows: D3S1298-D3S1260-(D3S966, D3S1448 (= D3S1449)-D3S1029-D3S32-D3S643-D3F15S2 -D3S2968-D3S1235-D3S1289-D3S1447-D3S1295.
从位于3p21远端到近端具有明确顺序的5个标记物开始，另外9个标记物可插入到这个3p21图谱中。其中5个通过遗传学方法进行了精确定位。其他标记物则通过荧光原位杂交（FISH）和/或缺失杂交图谱法进行排序。从远端到近端的3p21总体顺序如下：D3S1298-D3S1260-（D3S966，D3S1448（=D3S1449）-D3S1029-D3S32-D3S643-D3F15S2 -D3S2968-D3S1235-D3S1289-D3S1447-D3S1295。
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