Harada M
Dept. of Internal Medicine II, Okayama University Medical School.
Gan To Kagaku Ryoho. 1996 Dec;23(14):1877-85.
Allogeneic peripheral blood stem cell transplantation (allo-PBSCT) has been increasingly used as an alternative to allogeneic bone marrow transplantation (allo-BMT). In comparison with allo-BMT, preliminary results indicate that rapid hematopoietic engraftment can be obtained, and there is no increase in the incidence and severity of acute GVHD after allo-PBSCT. Furthermore, general anesthesia is not required to collect a sufficient number of PBSCT, which are usually mobilized by G-CSF administration. Therefore, allo-BMT will be replaced by allo-PBSCT in near future.
异基因外周血干细胞移植（allo-PBSCT）已越来越多地被用作异基因骨髓移植（allo-BMT）的替代方法。与allo-BMT相比，初步结果表明，allo-PBSCT可实现快速造血植入，且急性移植物抗宿主病（GVHD）的发生率和严重程度并无增加。此外，采集足够数量的PBSCT通常通过注射粒细胞集落刺激因子（G-CSF）来动员，无需全身麻醉。因此，allo-BMT在不久的将来将被allo-PBSCT所取代。
