Rakower S R
Surg Gynecol Obstet. 1977 Oct;145(4):555-8.
Anticoagulation largely prevents clotting and defibrination in extravascular blood pools. Systemic or local heparin may be more effective than local citrate phosphate dextrose in preventing coagulation in extravascular blood, if there is to be a lag period greater than 60 minutes between blood loss and collection. Nonanticoagulated extravascular blood in the thorax or peritoneal cavity is completely defibrinated within 20 minutes and is a potential risk in large autotransfusions. Blood in the thorax is better preserved than peritoneal blood after local or systemic heparinization.
抗凝在很大程度上可防止血管外血池中的凝血和纤维蛋白溶解。如果失血与采血之间的间隔时间超过60分钟，全身或局部使用肝素在预防血管外血液凝固方面可能比局部使用枸橼酸盐磷酸盐葡萄糖更有效。胸腔或腹腔内未抗凝的血管外血液在20分钟内会完全发生纤维蛋白溶解，这在大量自体输血中是一个潜在风险。局部或全身肝素化后，胸腔内的血液比腹腔内的血液保存得更好。
