Di Lorenzo G, Mansueto P, Melluso M, Sangiorgi G B, Cigna D, Candore G, Caruso C
Cattedra di Medicina Interna II, Istituto di Medicina Interna e Geriatria Università di Palermo, Italia.
Int Arch Allergy Immunol. 1997 Jan;112(1):93-5. doi: 10.1159/000237437.
We describe an HLA-B8, DR3-positive patient with localized morphea after silicone gel breast implantation for cosmetic reasons. We believe that this case suggests that a genetic background, i.e. HLA-B8, DR3 haplotype, is involved in the autoimmune response to silicone.
我们描述了一名因美容原因在硅胶乳房植入术后出现局限性硬皮病的HLA - B8、DR3阳性患者。我们认为该病例提示遗传背景,即HLA - B8、DR3单倍型,参与了对硅胶的自身免疫反应。