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从鸵鸟(鸵鸟属骆驼鸵鸟)中分离出副粘病毒血清型7。

Isolation of paramyxovirus serotype 7 from ostriches (Struthio camelus).

作者信息

Woolcock P R, Moore J D, McFarland M D, Panigrahy B

机构信息

California Veterinary Diagnostic Laboratory System-Fresno Branch, University of California, Davis 93725, USA.

出版信息

Avian Dis. 1996 Oct-Dec;40(4):945-9.

PMID:8980831
Abstract

Paramyxovirus serotype 7 (PMV-7) was isolated from pooled intestinal contents of two 5-month-old ostriches (Struthio camelus). The pathogenicity of the virus was comparable with lentogenic strains of Newcastle disease virus (PMV-1) in chicken and chicken embryo pathogenicity tests. The relationship of the virus to the observed pathology of proliferative nonsuppurative enteritis is unknown; the Campylobacter jejuni isolated was presumably the primary pathogen. To our knowledge, this is the first report of an isolation of PMV-7 from ostriches.

摘要

副粘病毒血清型7(PMV - 7)是从两只5个月大鸵鸟(鸵鸟属)的混合肠道内容物中分离出来的。在鸡和鸡胚致病性试验中,该病毒的致病性与新城疫病毒(PMV - 1)的弱毒株相当。该病毒与观察到的增生性非化脓性肠炎病理之间的关系尚不清楚;分离出的空肠弯曲菌可能是主要病原体。据我们所知,这是首次从鸵鸟中分离出PMV - 7的报告。

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Mutation of the f-protein cleavage site of avian paramyxovirus type 7 results in furin cleavage, fusion promotion, and increased replication in vitro but not increased replication, tissue tropism, or virulence in chickens.
禽类副黏病毒 7 型 f 蛋白裂解位点突变导致弗林蛋白酶裂解、融合促进以及体外复制增加,但不导致在鸡中的复制增加、组织嗜性或毒力增强。
J Virol. 2012 Apr;86(7):3828-38. doi: 10.1128/JVI.06765-11. Epub 2012 Jan 18.