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关于酒精相关神经发育障碍,动物研究告诉了我们什么。

What research with animals is telling us about alcohol-related neurodevelopmental disorder.

作者信息

Hannigan J H

机构信息

Wayne State University School of Medicine, C.S. Mott Center for Human Growth and Development, Department of Obstetrics & Gynecology, Detroit, MI 48201, USA.

出版信息

Pharmacol Biochem Behav. 1996 Dec;55(4):489-99. doi: 10.1016/s0091-3057(96)00251-1.

Abstract

The substantial advances in understanding fetal alcohol syndrome over the past 20 years were made in large part because of research with animals. This review illustrates recent progress in animal research by focusing primarily on the central nervous system effects of prenatal alcohol exposure. Current findings suggest further progress in understanding consequences, risk factors, mechanisms, prevention and treatment will depend on continued research with animals.

摘要

在过去20年里,对胎儿酒精综合征的认识取得了重大进展,这在很大程度上归功于动物研究。本综述主要关注产前酒精暴露对中枢神经系统的影响,以此阐述动物研究的最新进展。目前的研究结果表明,要在理解后果、风险因素、机制、预防和治疗方面取得进一步进展,将取决于对动物的持续研究。

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