• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

EI-1511-3、-5以及EI-1625-2，由链霉菌属E-1511和E-1625产生的新型白细胞介素-1β转化酶抑制剂。II. 结构测定。

EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. II. Structure determination.

作者信息

Uosaki Y, Agatsuma T, Tanaka T, Saitoh Y

机构信息

Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.

出版信息

J Antibiot (Tokyo). 1996 Nov;49(11):1079-84. doi: 10.7164/antibiotics.49.1079.

DOI:10.7164/antibiotics.49.1079
PMID:8982334
Abstract

The structures of three novel interleukin-1 beta converting enzyme inhibitors, EI-1511-3, -5 and EI-1625-2 were determined by spectroscopic methods. Their absolute configurations were also determined by analyses of the CD spectra of the inhibitors and their oxidation products with chromium trioxide.

摘要

通过光谱法确定了三种新型白细胞介素-1β转化酶抑制剂EI-1511-3、-5和EI-1625-2的结构。还通过分析抑制剂及其三氧化铬氧化产物的圆二色光谱确定了它们的绝对构型。

相似文献

1
EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. II. Structure determination.EI-1511-3、-5以及EI-1625-2，由链霉菌属E-1511和E-1625产生的新型白细胞介素-1β转化酶抑制剂。II. 结构测定。
J Antibiot (Tokyo). 1996 Nov;49(11):1079-84. doi: 10.7164/antibiotics.49.1079.
2
EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. I. Taxonomy of producing strain, fermentation and isolation.
J Antibiot (Tokyo). 1996 Nov;49(11):1073-8. doi: 10.7164/antibiotics.49.1073.
3
EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. III. Biochemical properties of EI-1511-3, -5 and EI-1625-2.
J Antibiot (Tokyo). 1996 Nov;49(11):1085-90. doi: 10.7164/antibiotics.49.1085.
4
EI-1941-1 and -2, novel interleukin-1beta converting enzyme inhibitors produced by Farrowia sp. E-1941. I. Biochemical characterization of EI-1941-1 and -2.
J Antibiot (Tokyo). 2003 May;56(5):464-9. doi: 10.7164/antibiotics.56.464.
5
EI-1941-1 and -2, novel interleukin-1 beta converting enzyme inhibitors Produced by Farrowia sp. E-1941. II. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties, and biological properties.
J Antibiot (Tokyo). 2003 Jul;56(7):603-9. doi: 10.7164/antibiotics.56.603.
6
EI-2346, a novel interleukin-1beta converting enzyme inhibitor produced by Streptomyces sp. E-2346. I. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties, and biological properties.
J Antibiot (Tokyo). 2003 Dec;56(12):985-92. doi: 10.7164/antibiotics.56.985.
7
EI-2346, a novel interleukin-1beta converting enzyme inhibitor produced by Streptomyces sp. E-2346. II. Structure elucidation.EI-2346，一种由链霉菌属E-2346产生的新型白细胞介素-1β转化酶抑制剂。II. 结构解析。
J Antibiot (Tokyo). 2004 Apr;57(4):289-90. doi: 10.7164/antibiotics.57.289.
8
EI-1507-1 and -2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1507.EI - 1507 - 1和 - 2，由链霉菌属E - 1507产生的新型白细胞介素 - 1β转化酶抑制剂。
J Antibiot (Tokyo). 1996 Apr;49(4):333-9. doi: 10.7164/antibiotics.49.333.
9
Total synthesis of the interleukin-1beta converting enzyme inhibitor EI-1941-2 using tandem oxa-electrocyclization/oxidation1.采用串联氧杂电环化/氧化反应全合成白细胞介素-1β转化酶抑制剂EI-1941-2 1。
Org Lett. 2006 Jun 22;8(13):2847-50. doi: 10.1021/ol060954f.
10
Enantio- and diastereoselective total synthesis of EI-1941-1, -2, and -3, inhibitors of interleukin-1beta converting enzyme, and biological properties of their derivatives.白细胞介素-1β转化酶抑制剂EI-1941-1、-2和-3的对映选择性和非对映选择性全合成及其衍生物的生物学性质
J Org Chem. 2005 Nov 25;70(24):9905-15. doi: 10.1021/jo0516436.

引用本文的文献

1
Small Molecule Active Site Directed Tools for Studying Human Caspases.用于研究人类半胱天冬酶的小分子活性位点导向工具
Chem Rev. 2015 Nov 25;115(22):12546-629. doi: 10.1021/acs.chemrev.5b00434. Epub 2015 Nov 9.
2
Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived Streptomyces sp.Carpatamides A-C，来自海洋来源的链霉菌属的细胞毒性芳基胺衍生物。
J Nat Prod. 2014 May 23;77(5):1245-8. doi: 10.1021/np500207p. Epub 2014 Apr 23.