Hayakawa T, Waltz A G
Stroke. 1977 Jul-Aug;8(4):421-6. doi: 10.1161/01.str.8.4.421.
Devices to produce experimental subarachnoid hemorrhage (SAH) can be implanted in animals. After SAH is produced by the puncture of a middle cerebral artery (MCA) in awake cats, neurologic deficits develop that are not as severe as those caused by MCA occlusion. Biphasic increases of epidural pressure occur and are related to the extent and distribution of the hemorrhage. Ischemic changes are more severe if the flow of blood through the MCA is interrupted.
可在动物体内植入用于产生实验性蛛网膜下腔出血(SAH)的装置。在清醒猫的大脑中动脉(MCA)穿刺导致SAH后,会出现神经功能缺损,但其严重程度不如MCA闭塞所致的神经功能缺损。硬膜外压力呈双相增加,且与出血的范围和分布有关。如果MCA的血流中断,缺血性改变会更严重。