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[眼部过敏观察站。眼科所见慢性(常年性)过敏性结膜炎和/或角结膜炎的全国性流行病学调查]

[Observatoire des Allergies Oculaires. National epidemiological survey of chronic (perennial) allergic conjunctivitis and/or keratoconjunctivitis seen in ophthalmology].

作者信息

Bloch-Michel E, Vérin P, Dibie A

机构信息

Centre d'Allergie, Hôpital Rothschild, Paris.

出版信息

Allerg Immunol (Paris). 1996 Sep;28(7):234-41.

PMID:8983239
Abstract

A second epidemiological ocular allergy survey was carried out by ophthalmologists during the winter of 94/95 in order to define the main characteristics of patients suffering from chronic, perennial allergic conjunctivitis or keratoconjunctivitis. From the data collected from a wide sample of 791 patients, we were able to describe the main symptoms and lesions related to chronic ocular allergy, its evolution and the allergens involved. Allergic symptoms (conjunctival redness, foreign body sensation, itching) are reported in 98.5% of patients. Non specific symptoms (burning, photophobia, blurred vision, ocular dryness) are reported in 3 patients out of 4. 40% of patients have perennial manifestations without any seasonal exacerbation while 1 patient in 2 suffers from a seasonal worsening. In 80% of the cases, the responsible allergens are domestic (house dust, miles), 60% of patients are affected by at least 2 allergens. Ophthalmic examination shows lesions of the tarsal conjunctiva (papillas, follicles) in 94% of the cases and corneal lesions in practically 50% of the patients. This epidemiological survey shows the necessity of having a rigourous clinical approach which includes a complete ophthalmological examination which is the only thorough means of assessing the allergic lesions and proposing the most suitable treatment for day to day ophthalmic practice.

摘要

94/95年冬季,眼科医生开展了第二项眼部过敏流行病学调查,以确定患有慢性常年性过敏性结膜炎或角结膜炎患者的主要特征。通过对791名患者的大量样本收集的数据,我们能够描述与慢性眼部过敏相关的主要症状和病变、其演变过程以及所涉及的过敏原。98.5%的患者报告有过敏症状(结膜充血、异物感、瘙痒)。四分之三的患者报告有非特异性症状(烧灼感、畏光、视力模糊、眼干)。40%的患者有常年性症状,无任何季节性加重,而二分之一的患者有季节性恶化。在80%的病例中,致病过敏原是室内的(屋尘、螨虫),60%的患者至少受两种过敏原影响。眼科检查显示,94%的病例有睑结膜病变(乳头、滤泡),近50%的患者有角膜病变。这项流行病学调查表明,需要采取严格的临床方法,包括全面的眼科检查,这是评估过敏性病变并为日常眼科实践提出最合适治疗方法的唯一彻底手段。

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