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[门诊尿路感染的细菌学与耐药性]

[Bacteriology and resistance in ambulatory urinary infections].

作者信息

Villar Gil J, Baeza Berruti J E, de Diego Sierra D, Ruiz-Poveda García-Rojo A, González Rodríguez J C, Barba Ferreras I

机构信息

Unidad Docente de Medicina Familiar y Communitaria de Ciudad Real.

出版信息

Aten Primaria. 1996 Oct 15;18(6):315-7.

PMID:8983385
Abstract

OBJECTIVES

To discover the bacteriological profile of urinary tract infections (UTI) in our out-clinic environment and their resistance to the most common antibiotics.

DESIGN

A descriptive, retrospective study.

SETTING

Ciudad Real Health Area (300,000 inhabitants).

PARTICIPANTS

All the urine samples from the out-clinics referred to the microbiology lab for possible UTI in 1994 were included.

MEASUREMENTS AND MAIN RESULTS

3,522 cultures were studied, of which 241 were contaminated (7%), 2,870 negative (81%) and 409 positive (12%). Breakdown of bacteria: E. coli (248; 60%), enterococci (38; 9%), P. mirabilis (25; 6%), K. pneumoniae (20; 5%), S. epidermidis (11;3%), S. saprophyticus (8; 2%) and 61 others (15%). We found high sensitivity in the Gram-negatives to cephuroxim and amoxicillin-clavulanic. We observed widespread resistance, especially by E. coli, to quinolones, pipemidic acid and nitrofurantoin.

CONCLUSIONS

E. coli is the micro-organism which most often causes UTI in our environment. We found enterococci were isolated more and S. saprophyticus less than in the series consulted. We found a considerable increase in resistance to some antibiotics often used in out-clinics for UTI treatment.

摘要

目的

了解我院门诊环境下尿路感染(UTI)的细菌学特征及其对最常用抗生素的耐药性。

设计

描述性回顾性研究。

地点

雷阿尔城健康区(30万居民)。

研究对象

纳入1994年门诊送检微生物实验室的所有可能为UTI的尿液样本。

测量指标及主要结果

共研究3522份培养物,其中241份污染(7%),2870份阴性(81%),409份阳性(12%)。细菌分类:大肠杆菌(248株;60%)、肠球菌(38株;9%)、奇异变形杆菌(25株;6%)、肺炎克雷伯菌(20株;5%)、表皮葡萄球菌(11株;3%)、腐生葡萄球菌(8株;2%)及其他61株(15%)。革兰阴性菌对头孢呋辛和阿莫西林-克拉维酸敏感性高。观察到广泛耐药,尤其是大肠杆菌对喹诺酮类、吡哌酸和呋喃妥因耐药。

结论

在我院环境中,大肠杆菌是最常引起UTI的微生物。我们发现肠球菌分离株较参考系列更多,腐生葡萄球菌更少。我们发现门诊治疗UTI常用的一些抗生素耐药性显著增加。

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