Kostiuk I F, Kapustnik V A
Lik Sprava. 1995 Sep-Dec(9-12):157-60.
Effectiveness was studied of two drug preparations of calcium antagonists CAs group: cordaphene (30 mg) and diltiazeme (180 mg) in patients with vibration disease (VD) due to local vibration. CAs were shown to exert peripheral vasodilating, membrane-protecting and antioxidant effects. Cordaphene appeared to have a most pronounced CAs effect. We should advise its prescription preferably in those VD patients presenting with concomitant arterial hypertension.
研究了两种钙拮抗剂（CAs）类药物制剂：可多芬（30毫克）和地尔硫䓬（180毫克）对局部振动引起的振动病（VD）患者的疗效。结果表明，CAs具有外周血管舒张、膜保护和抗氧化作用。可多芬似乎具有最显著的CAs效应。我们建议，对于伴有动脉高血压的VD患者，最好开具可多芬的处方。
