Blaauwwiekel E E, Zijlstra J G
Academisch Ziekenhuis, afd. Interne Geneeskunde, Intensive Care Beademing, Groningen.
Ned Tijdschr Geneeskd. 1996 Nov 2;140(44):2193-5.
A 50-year-old woman who received a prescription for hydrochlorothiazide for 'swollen ankles', developed respiratory distress due to acute pulmonary oedema within a few hours after she took the first dose. She was treated with artificial respiration during 3 days and with dopamine and circulatory volume suppletion. She recovered completely. Patient had stopped earlier use of hydrochlorothiazide because of respiratory discomfort. The described adverse effect is rare, but because of the high use of this drug it is important to recognize it.
一名50岁女性因“脚踝肿胀”收到氢氯噻嗪处方,在服用首剂后数小时内因急性肺水肿出现呼吸窘迫。她接受了3天的人工呼吸以及多巴胺治疗和补充循环血容量,最终完全康复。该患者此前因呼吸不适已停用氢氯噻嗪。所述不良反应较为罕见,但鉴于该药物使用广泛,认识到这一点很重要。