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[土耳其斯坦东毕吸虫对牛肝脏磷脂状态的影响]

[Modification of the liver phospholipid status of cattle by Orientobilharzia turkestanica trematodes].

作者信息

Oĭmatov M, Shakarbaev E B, Zaitova A Z

出版信息

Parazitologiia. 1996 Sep-Oct;30(5):460-3.

PMID:8984448
Abstract

The paper gives the data on a trematode influence onto the phospholipid (PL) contents in the liver of cows. It is shown, that the decrease of PL basic fraction concentrations, i.e. phosphatidilcholin (PC) by 20% and phosphotidilethanolamin (PE) by 26%, during the period of infection is accompanied by the increase of respective lysoforms, namely, lysoPC by 240%, and lysoPE by 160%, and as well as minor forms, PL-diphosphotidilgleserol by 70%, sphingomielin by 47% and phosphatidilserin by 41%. It is suggested, that the infection of cow liver by trematodes determines such contents and principles of membrane structures, which decrease their functional activity and probably increase its permeability for ions, some metabolites and low molecular carbohydrates.

摘要

该论文给出了关于吸虫对奶牛肝脏中磷脂(PL)含量影响的数据。结果表明,在感染期间,PL主要组分浓度降低,即磷脂酰胆碱(PC)降低20%,磷脂酰乙醇胺(PE)降低26%,同时相应的溶血形式增加,即溶血磷脂酰胆碱(lysoPC)增加240%,溶血磷脂酰乙醇胺(lysoPE)增加160%,以及次要形式,磷脂二磷脂酰甘油(PL-diphosphotidilgleserol)增加70%,鞘磷脂增加47%,磷脂酰丝氨酸增加41%。研究表明,吸虫感染奶牛肝脏决定了膜结构的这种含量和组成原则,这降低了它们的功能活性,并可能增加其对离子、一些代谢物和低分子碳水化合物的通透性。

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