Goday-Arnó A, García Rico A, Martínez-Riquelme A, Cano-Pérez J F
Servicio de Endocrinología, Hospital Universitario del Mar, Barcelona.
Rev Clin Esp. 1996 Aug;196(8):536-8.
Two cases are reported of women aged 18 and 36 years respectively who developed a typical picture of hyperthyroidism by Graves Basedow disease (primary hyperthyroidism, diffuse goiter with increased uptake, positive stimulating thyroid antibodies, exophthalmos). These women had taken drugs for obesity which were prepared by magistral formula and acquired by mail 8 and 9 months prior to diagnosis of the disease. The differential diagnosis is discussed which should be considered in a women with hyperthyroidism and the antecedent of ingestion of weight-reducer drugs as well as the orientative data of the different causes. Also, the possible role of these drugs as triggering factor for the autoimmune thyroid disease is discussed.
报告了两例分别为18岁和36岁的女性病例，她们因格雷夫斯病（原发性甲状腺功能亢进、弥漫性甲状腺肿伴摄取增加、甲状腺刺激抗体阳性、突眼）出现典型的甲状腺功能亢进症状。这些女性在疾病诊断前8个月和9个月服用了由药房配方制备并通过邮寄获得的减肥药。文中讨论了对于患有甲状腺功能亢进且有服用减肥药史的女性应考虑的鉴别诊断以及不同病因的相关参考数据。此外，还讨论了这些药物作为自身免疫性甲状腺疾病触发因素的可能作用。
