Lee J, Nunn J, Wright C
Northumberland Community Health NHS Trust, Gateshead.
Arch Dis Child. 1996 Oct;75(4):327-9. doi: 10.1136/adc.75.4.327.
Growth was studied in 83 children with cleft lip and/or palate aged 0-4 years attending a specialist regional centre. Information was collected by a personal interview, postal questionnaire, and record review. The group as a whole grew relatively poorly in early infancy but subsequently recovered, attaining both expected weight and height by last follow up at age 25.5 months (range 3 to 47). However, the group proved heterogeneous, with children with isolated clefts of the secondary palate showing the most abnormal growth. Children with underlying syndromes were significantly more likely to be short at follow up, while type or severity of cleft was not significantly related to follow up height. Therefore, while cleft palate was associated with significant growth faltering in early infancy, rapid recovery took place following surgical repair and appears to have resulted in no residual growth deficit.
对83名年龄在0至4岁、前往某专科地区中心就诊的唇裂和/或腭裂患儿的生长情况进行了研究。通过个人访谈、邮寄问卷和病历审查收集信息。总体而言,该组患儿在婴儿早期生长相对较差,但随后恢复,到25.5个月(范围为3至47个月)的最后一次随访时达到了预期的体重和身高。然而,该组结果显示存在异质性,继发腭裂单独发病的患儿生长异常最为明显。患有潜在综合征的患儿在随访时明显更易出现身材矮小,而腭裂的类型或严重程度与随访时的身高无显著相关性。因此,虽然腭裂与婴儿早期显著的生长发育迟缓有关,但手术修复后恢复迅速,且似乎没有导致残留的生长缺陷。