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[口服地西泮间歇性预防高热惊厥:82例研究]

[Intermittent prophylaxis in febrile seizures with oral diazepam: study of 82 cases].

作者信息

Costa M, Silva E A, Silva A E, Guerreiro M M

机构信息

Departamento de Neurologia, Universidade Estadual de Campinas, Brasil.

出版信息

Arq Neuropsiquiatr. 1996 Jun;54(2):197-201. doi: 10.1590/s0004-282x1996000200003.

Abstract

We present our results of intermittent prophylaxis with oral diazepam in febrile seizures. We treated 82 patients aged between 3 months and 5 years. They have had simple or complex febrile seizures. Recurrence occurred in 22 patients (26%), none had a long-lasting febrile convulsion. Transient side effects occurred in 21.95% of the cases. We conclude that diazepam is a safe and effective drug for prophylaxis of febrile seizures when used as soon as any sign of illness appears. We suggest, however, that the administration of the drug should be indicated if the child presents at least one consistent predictor of risk of recurrent febrile seizures.

摘要

我们展示了口服地西泮间歇性预防高热惊厥的结果。我们治疗了82名年龄在3个月至5岁之间的患者。他们曾发生过单纯性或复杂性高热惊厥。22名患者(26%)出现复发,无一人发生长时间高热惊厥。21.95%的病例出现短暂副作用。我们得出结论,地西泮在疾病任何迹象一出现时就使用,是预防高热惊厥的一种安全有效的药物。然而,我们建议,如果儿童至少有一个复发性高热惊厥风险的一致预测指标,就应使用该药。

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