Torres L F, Medeiros B C, Noronha L, Pedroso A, Ramina R
Seção de Microscopia Eletrônica e Neuropatologia, Universidade Federal do Paraná, Curitiba.
Arq Neuropsiquiatr. 1996 Jun;54(2):280-3. doi: 10.1590/s0004-282x1996000200015.
Optic nerve gliomas may occur alone or as components of neurofibromatosis. They are rare tumors accounting for 2 to 5% of all intracranial tumors and 6% of the intra-orbitary neoplasms. The authors present 11 cases of optic nerve-glioma diagnosed in Curitiba in the last 25 years. Out of these 11 patients there were 10 women and only 1 man. The ages ranged from 3 to 25 years old, and 6 patients were under 15 years. In this series, 27.3% (n = 3) of the cases were associated with neurofibromatosis. Five patients had their tumors restricted to the optic nerve while the others had either extension to the optic chiasm, supra-selar region, frontal or temporal lobe. All the patients had pilocytic astrocytomas.
视神经胶质瘤可单独发生,也可作为神经纤维瘤病的组成部分。它们是罕见肿瘤,占所有颅内肿瘤的2%至5%,眼眶内肿瘤的6%。作者介绍了过去25年在库里蒂巴诊断出的11例视神经胶质瘤病例。在这11名患者中,有10名女性,只有1名男性。年龄范围为3至25岁,6名患者年龄在15岁以下。在这个系列中,27.3%(n = 3)的病例与神经纤维瘤病有关。5名患者的肿瘤局限于视神经,而其他患者的肿瘤则扩展至视交叉、鞍上区域、额叶或颞叶。所有患者均患有毛细胞型星形细胞瘤。