Papasian C J, Kinney J, Coffman S, Hollis R J, Pfaller M A
Department of Pathology, Truman Medical Center University of Missouri, School of Medicine, Kansas City 64108, USA.
Diagn Microbiol Infect Dis. 1996 Oct;26(2):63-7. doi: 10.1016/s0732-8893(96)00177-0.
We describe a case in which Citrobacter koseri (formerly C. diversus) was transmitted from a pregnant mother with chorioamnionitis and bacteremia to her infant who was bacteremic at birth and in apparent septic shock. Two highly discriminating molecular methods, ribotyping and pulsed field gel electrophoresis, were used to examine restriction fragment length polymorphisms within the genomic DNA of maternal and infant isolates. Both techniques identified the maternal and infant isolates as the same strain, distinct from epidemiologically unrelated controls, thus confirming their common origin.
一名患有绒毛膜羊膜炎和菌血症的孕妇将科氏柠檬酸杆菌（以前称为差异柠檬酸杆菌）传染给了她出生时即发生菌血症且明显处于感染性休克状态的婴儿。采用两种高分辨率分子方法，即核糖体分型和脉冲场凝胶电泳，来检测母婴分离株基因组DNA内的限制性片段长度多态性。两种技术均鉴定出母婴分离株为同一菌株，与流行病学上无关的对照菌株不同，从而证实了它们的共同来源。
