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空中救护转运过程中心输出量的变化。

Changes in cardiac output during air ambulance repatriation.

作者信息

Malagon I, Grounds R M, Bennett E D

机构信息

UMDS Division of Anaesthetics, Guy's Hospital, London, UK.

出版信息

Intensive Care Med. 1996 Dec;22(12):1396-9. doi: 10.1007/BF01709557.

DOI:10.1007/BF01709557
PMID:8986492
Abstract

OBJECTIVES

To measure, with the use of suprasternal Doppler ultrasound, the hemodynamic changes in patients and volunteers during air ambulance repatriation.

DESIGN

Unblinded prospective observational study.

SETTING

Chartered air ambulances for the international repatriation of patients.

PATIENTS AND PARTICIPANTS

Six medical crew members and seven patients transported back to hospitals in the UK.

INTERVENTIONS

The measurement of non-invasive blood pressure, ECG, heart rate, oxygen saturation and hemodynamic variables with suprasternal Doppler.

MEASUREMENTS AND RESULTS

There was a drop in systolic and mean arterial blood pressure in the patient's group once in the air. Oxygen saturation dropped in both groups once at cruising altitude. Heart rate remained unchanged. Stroke distance and minute distance increased significantly in the patient's group and non-significantly in the volunteers. Peak velocity increased significantly in the patient's group. There was an overall reduction of systemic vascular resistance during take off and once at cruising altitude.

CONCLUSIONS

Hemodynamic changes happen during air ambulance transportation in fit and healthy volunteers and patients alike. These may be due to a combination of hypobaric hypoxia and gravitational forces. It is necessary to establish if these changes have short- or long-term effects in the critically ill.

摘要

目的

使用胸骨上多普勒超声测量患者和志愿者在航空医疗转运回国过程中的血流动力学变化。

设计

非盲前瞻性观察性研究。

地点

用于患者国际转运回国的包机航空医疗服务。

患者和参与者

6名医护人员以及7名被转运回英国医院的患者。

干预措施

使用胸骨上多普勒测量无创血压、心电图、心率、血氧饱和度和血流动力学变量。

测量结果

患者组在空中时收缩压和平均动脉压下降。两组在巡航高度时血氧饱和度均下降。心率保持不变。患者组的每搏输出量和每分钟输出量显著增加,志愿者组增加不显著。患者组的峰值速度显著增加。起飞期间及到达巡航高度后全身血管阻力总体下降。

结论

健康志愿者和患者在航空医疗转运过程中均会出现血流动力学变化。这些变化可能是由于低压缺氧和重力共同作用所致。有必要确定这些变化对危重症患者是否有短期或长期影响。

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本文引用的文献

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Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia.暴露于低氧环境的人内皮细胞对前列腺素合成的刺激作用。
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Hemodynamic effects of altitude exposure and oxygen administration in chronic obstructive pulmonary disease.海拔暴露和吸氧对慢性阻塞性肺疾病的血流动力学影响
Am J Med. 1993 Apr;94(4):407-12. doi: 10.1016/0002-9343(93)90152-f.
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Comparison of cardiac output measurement techniques: thermodilution, Doppler, CO2-rebreathing and the direct Fick method.
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Air travel and oxygen therapy in cardiopulmonary patients.
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Short-term adaptation to moderate altitude. Patients with chronic obstructive pulmonary disease.对中度海拔的短期适应。慢性阻塞性肺疾病患者。
JAMA. 1978 Sep 29;240(14):1491-4.