Parsons B J, Day L M, Ozanne-Smith J, Dobbin M
Pharmacy Department, Royal Children's Hospital, Melbourne.
Aust N Z J Public Health. 1996 Oct;20(5):488-92. doi: 10.1111/j.1467-842x.1996.tb01627.x.
We aimed to determine the nature, extent and sequence of events of accidental childhood poisoning with rodenticides and identify potential intervention strategies. Subjects were identified prospectively from callers to the Victorian Poisons Information Centre and those presenting to the Emergency Departments of hospitals participating in the Victorian Injury Surveillance System from 1 April to 31 December 1993. The events preceding rodenticide ingestion were examined via telephone questionnaire involving 128 parents or guardians of children under five years exposed to rodenticides. Rodenticides are not leading agents for severe poisoning but are a frequent and increasing cause of less severe poisoning. Most children (90 per cent) had obtained the rodenticide from the site at which it had been laid, usually by the caregiver (67 per cent), in the kitchen, lounge room or laundry, inside cupboards or-wardrobes. In 69 per cent of these cases, respondents thought the site would not normally allow access to children. Only 13 per cent of children were admitted to hospital, although 41 per cent sought medical attention. Most caregivers (90 per cent) were aware of some dangers associated with rodenticides. Children usually ingest insufficient amounts of rodenticide to cause serious effects. However, medical assessment and monitoring of prothrombin times is often indicated, with a consequent cost to the healthcare system. Potential countermeasures, focusing on packaging and positioning of rodenticide baits, product reformulation, and the distribution of management guidelines for health workers, were identified. Implementation of the identified countermeasures was initiated by a workshop involving stakeholders from industry, research and health professions.
我们旨在确定儿童意外摄入灭鼠剂事件的性质、程度和事件顺序,并确定潜在的干预策略。从致电维多利亚州毒物信息中心的人员以及1993年4月1日至12月31日期间前往参与维多利亚州伤害监测系统的医院急诊科就诊的人员中前瞻性地确定研究对象。通过电话问卷调查对128名五岁以下接触灭鼠剂儿童的父母或监护人进行调查,以了解摄入灭鼠剂之前发生的事件。灭鼠剂并非严重中毒的主要原因,但却是轻度中毒的常见且日益增多的原因。大多数儿童(90%)是从放置灭鼠剂的地点获取到灭鼠剂的,通常是由照顾者(67%)在厨房、客厅或洗衣房,橱柜或衣柜内获取的。在这些案例中,69%的受访者认为该地点通常不会让儿童接触到。只有13%的儿童住院治疗,尽管41%的儿童寻求了医疗救治。大多数照顾者(90%)意识到了与灭鼠剂相关的一些危险。儿童通常摄入不足量的灭鼠剂而不会造成严重影响。然而,通常需要对凝血酶原时间进行医学评估和监测,这会给医疗系统带来成本。已确定了潜在的应对措施,重点是灭鼠剂诱饵包装和放置、产品重新配方以及为卫生工作者分发管理指南。由来自行业、研究和卫生专业的利益相关者参加的研讨会启动了已确定应对措施的实施。