Gorodilova V V, Iatskovskaia N L
Vopr Onkol. 1977;23(3):9-12.
Under study were immunological indices--the reaction of microprecipitation (tumor and embryonal antigens) and HRDT (tumor and tuberculine antigens) in 305 patients with cancer of the uterine cervix. It was found that most patients showed impaired immune responses: an increased number of persons with specific antibodies circulating in blood serum and increased hypersensitivity of of delayed type. The percentage of positive reactions of microprecipitation and HRDT increases as the tumor spreads. The methods of combined therapy generally improve immunological indices, however, the process starts 1-3 years following the treatment.
对305例宫颈癌患者的免疫指标进行了研究,包括微量沉淀反应(肿瘤和胚胎抗原)和HRDT(肿瘤和结核菌素抗原)。结果发现,大多数患者的免疫反应受损:血清中循环特异性抗体的人数增加,迟发型超敏反应增强。微量沉淀反应和HRDT的阳性反应百分比随肿瘤扩散而增加。联合治疗方法通常能改善免疫指标,然而,这一过程在治疗后1至3年开始。