Gorodilova V V, Iatskovskaia N L
Vopr Onkol. 1978;24(3):10-3.
Under study were the factors of antitumor immunity (RHDT, the reaction of microprecipitation, the functional activity of lymphocytes, RFC and RBT) in 104 patients with cancer of the corpus uteri. It was found that most patients show an impaired immunobiological response, manifested in higher percentage of positive results with RHDT performed with the tumor antigen, and the reaction of microprecipitation with tumor and embryonal antigens, more week RFC and RBT. Immunological indices are getting worse with the process spread and are improved following the combination therapy. The process of treatment however (surgery and radiotherapy) renders a negative effect on immune indices. Normalization of the latter is noted not earlier than 1-3 years after the treatment.
对104例子宫体癌患者的抗肿瘤免疫因素(玫瑰花环抑制试验、微量沉淀反应、淋巴细胞功能活性、玫瑰花环形成细胞和玫瑰花环结合细胞)进行了研究。发现大多数患者表现出免疫生物学反应受损,表现为用肿瘤抗原进行玫瑰花环抑制试验、与肿瘤和胚胎抗原的微量沉淀反应的阳性结果百分比更高,玫瑰花环形成细胞和玫瑰花环结合细胞数量更少。随着病情进展,免疫指标恶化,联合治疗后有所改善。然而,治疗过程(手术和放疗)对免疫指标产生负面影响。治疗后1至3年才观察到后者恢复正常。