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BS II凝集素:从单叶豆种子中分离出的第二种血凝素,对III型可多凝集红细胞具有亲和力。

BS II lectin: a second hemagglutinin isolated from Bandeiraea simplicifolia seeds with affinity for type III polyagglutinable red cells.

作者信息

Judd W J, Beck M L, Hicklin B L, Iyer P N, Goldstein I J

出版信息

Vox Sang. 1977 Oct;33(4):246-51. doi: 10.1111/j.1423-0410.1977.tb04469.x.

Abstract

BS II lectin, a second hemagglutinin isolated from Bandeiraea simplicifolia seeds, agglutinated the red cells from 11 patients manifesting the 'acquired B' antigen phenomenon. The results of serological studies indicate that this lectin has specificity for the type III polyagglutinable receptors rather than for the 'B-like' antigens present on 'acquired B' red cells. Two other blood samples which did not possess 'acquired B' antigens were also found to react with BS II lectin. Both of these samples were shown to have properties similar to those reported for Tk red cells. The serological characteristics of red cells modified in vitro by a culture broth of Bacteroides fragilis suggest that type III polyagglutinable receptors are identical to those associated with Tk red cells.

摘要

BS II凝集素是从单叶豆种子中分离出的第二种血凝素,它能凝集11例表现出“获得性B”抗原现象患者的红细胞。血清学研究结果表明,这种凝集素对III型多凝集性受体具有特异性,而非对“获得性B”红细胞上存在的“类B”抗原具有特异性。还发现另外两份不具有“获得性B”抗原的血样也与BS II凝集素发生反应。这两份血样均显示出与报道的Tk红细胞具有相似的特性。脆弱拟杆菌培养液在体外修饰的红细胞的血清学特征表明,III型多凝集性受体与Tk红细胞相关的受体相同。

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