Terasaki H, Kikuchi S, Hoshi S
Department of Ophthalmology, Nagoya University School of Medicine, Japan.
Jpn J Ophthalmol. 1996;40(3):385-9.
Waldenström's macroglobulinemia is a malignant disease of the reticuloendothelial system; ocular complications reported previously have been concerned chiefly with hyperviscosity manifestations. Ophthalmic tumor formation is rare, although not unheard of, in this particular condition. This report describes two rare instances of Waldenström's macroglobulinemia which involved conjunctival and orbital tumors. One patient developed the tumors after a lengthy clinical course; in the other patient, eyelid and orbital tumors were the first symptoms. Careful examination of the external eye, especially the fornix of the conjunctiva, in patients with Waldenström's macroglobulinemia can identify an initial lesion or invasions to other organs.
华氏巨球蛋白血症是一种网状内皮系统的恶性疾病；先前报道的眼部并发症主要与高黏滞血症表现有关。在这种特殊情况下，眼部肿瘤形成虽然并非闻所未闻，但较为罕见。本报告描述了两例罕见的华氏巨球蛋白血症病例，均累及结膜和眼眶肿瘤。一名患者在漫长的临床病程后出现肿瘤；另一名患者则以眼睑和眼眶肿瘤为首发症状。对华氏巨球蛋白血症患者进行仔细的眼部检查，尤其是结膜穹窿部检查，可发现初始病变或其他器官的侵犯情况。
