• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

大肠杆菌阳性调节因子OmpR在假定的RNA聚合酶相互作用位点处具有一个大的环状结构。

Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.

作者信息

Kondo H, Nakagawa A, Nishihira J, Nishimura Y, Mizuno T, Tanaka I

出版信息

Nat Struct Biol. 1997 Jan;4(1):28-31. doi: 10.1038/nsb0197-28.

DOI:10.1038/nsb0197-28
PMID:8989318
Abstract

The C-terminal DNA-binding domain of OmpR, a positive regulator involved in osmoregulation expression of the ompF and ompC genes in Escherichia coli, has a helix-turn-helix variant motif. The 'turn' region, consisting of 11 residues, forms an RNA polymerase contact site.

摘要

OmpR是一种参与大肠杆菌中ompF和ompC基因渗透调节表达的正调控因子，其C端DNA结合结构域具有一种螺旋-转角-螺旋变体基序。由11个残基组成的“转角”区域形成一个RNA聚合酶接触位点。

相似文献

1
Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.大肠杆菌阳性调节因子OmpR在假定的RNA聚合酶相互作用位点处具有一个大的环状结构。
Nat Struct Biol. 1997 Jan;4(1):28-31. doi: 10.1038/nsb0197-28.
2
The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor.OmpR的DNA结合结构域：一种翼状螺旋转录因子的晶体结构
Structure. 1997 Jan 15;5(1):109-24. doi: 10.1016/s0969-2126(97)00170-6.
3
Suppressor mutations in alpha-subunit of RNA polymerase for a mutant of the positive regulator, OmpR, in Escherichia coli.
FEMS Microbiol Lett. 1996 Jun 1;139(2-3):175-80. doi: 10.1111/j.1574-6968.1996.tb08199.x.
4
Structural comparison of the PhoB and OmpR DNA-binding/transactivation domains and the arrangement of PhoB molecules on the phosphate box.PhoB和OmpR DNA结合/反式激活结构域的结构比较以及PhoB分子在磷酸盒上的排列
J Mol Biol. 2000 Feb 4;295(5):1225-36. doi: 10.1006/jmbi.1999.3379.
5
A phosphorylation site mutant of OmpR reveals different binding conformations at ompF and ompC.OmpR的磷酸化位点突变体在ompF和ompC处显示出不同的结合构象。
J Mol Biol. 2002 Jan 25;315(4):497-511. doi: 10.1006/jmbi.2001.5222.
6
Crystallization and X-ray studies of the DNA-binding domain of OmpR protein, a positive regulator involved in activation of osmoregulatory genes in Escherichia coli.
J Mol Biol. 1994 Jan 14;235(2):780-2. doi: 10.1006/jmbi.1994.1032.
7
Location of DNA-binding segment of a positive regulator, OmpR, involved in activation of the ompF and ompC genes of Escherichia coli.参与激活大肠杆菌ompF和ompC基因的正向调节因子OmpR的DNA结合区段的定位。
FEBS Lett. 1988 Dec 19;242(1):27-30. doi: 10.1016/0014-5793(88)80978-5.
8
Gene activation by the Escherichia coli positive regulator OmpR: a mutational study of the DNA-binding domain of OmpR.大肠杆菌正向调节因子OmpR介导的基因激活：OmpR DNA结合结构域的突变研究
Mol Gen Genet. 1995 Aug 30;248(4):399-406. doi: 10.1007/BF02191639.
9
OmpR mutants specifically defective for transcriptional activation.对转录激活有特异性缺陷的OmpR突变体。
J Mol Biol. 1994 Nov 4;243(4):579-94. doi: 10.1016/0022-2836(94)90033-7.
10
Recognition of promoter DNA by subdomain 4.2 of Escherichia coli sigma 70: a knowledge based model of -35 hexamer interaction with 4.2 helix-turn-helix motif.大肠杆菌σ70亚结构域4.2对启动子DNA的识别：基于知识的-35六聚体与4.2螺旋-转角-螺旋基序相互作用模型
J Biomol Struct Dyn. 1997 Feb;14(4):407-19. doi: 10.1080/07391102.1997.10508140.

引用本文的文献

1
Metal Messengers: Communication in the Bacterial World through Transition-Metal-Sensing Two-Component Systems.金属信使：细菌世界中通过过渡金属感应双组分系统的通讯。
Biochemistry. 2023 Aug 15;62(16):2339-2357. doi: 10.1021/acs.biochem.3c00296. Epub 2023 Aug 4.
2
Promiscuity of response regulators for thioredoxin steers bacterial virulence.转录调控因子对硫氧还蛋白的滥用控制着细菌的毒力。
Nat Commun. 2022 Oct 20;13(1):6210. doi: 10.1038/s41467-022-33983-6.
3
The Odyssey of the Ancestral Escherich Strain through Culture Collections: an Example of Allopatric Diversification.
埃希氏菌属始祖菌株在菌种保藏中心的历程：异地多样化的一个实例
mSphere. 2018 Jan 31;3(1). doi: 10.1128/mSphere.00553-17. eCollection 2018 Jan-Feb.
4
Genome-Wide Screening Identifies Six Genes That Are Associated with Susceptibility to Escherichia coli Microcin PDI.全基因组筛选鉴定出六个与对大肠杆菌微菌素PDI易感性相关的基因。
Appl Environ Microbiol. 2015 Oct;81(20):6953-63. doi: 10.1128/AEM.01704-15. Epub 2015 Jul 24.
5
The Amino Acid Arginine 210 of the Response Regulator HrpG of Xanthomonas citri subsp. citri Is Required for HrpG Function in Virulence.柑橘黄龙病菌响应调节因子HrpG的第210位氨基酸精氨酸是HrpG在毒力方面发挥功能所必需的。
PLoS One. 2015 May 11;10(5):e0125516. doi: 10.1371/journal.pone.0125516. eCollection 2015.
6
Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms.革兰氏阴性菌中的银抗性：内源性和外源性机制剖析
J Antimicrob Chemother. 2015 Apr;70(4):1037-46. doi: 10.1093/jac/dku523. Epub 2015 Jan 6.
7
Atypical response regulator ChxR from Chlamydia trachomatis is structurally poised for DNA binding.沙眼衣原体非典型反应调节蛋白 ChxR 构象上适合与 DNA 结合。
PLoS One. 2014 Mar 19;9(3):e91760. doi: 10.1371/journal.pone.0091760. eCollection 2014.
8
The post-transcriptional regulator rsmA/csrA activates T3SS by stabilizing the 5' UTR of hrpG, the master regulator of hrp/hrc genes, in Xanthomonas.转录后调节因子 rsmA/csrA 通过稳定黄单胞菌中 hrp/hrc 基因的主调控因子 hrpG 的 5'UTR，激活 T3SS。
PLoS Pathog. 2014 Feb 27;10(2):e1003945. doi: 10.1371/journal.ppat.1003945. eCollection 2014 Feb.
9
Complement-mediated opsonization of invasive group A Streptococcus pyogenes strain AP53 is regulated by the bacterial two-component cluster of virulence responder/sensor (CovRS) system.补体介导的侵袭性 A 组链球菌 AP53 菌株的调理作用受细菌双组分毒力应答/传感器（CovRS）系统调节。
J Biol Chem. 2013 Sep 20;288(38):27494-27504. doi: 10.1074/jbc.M113.494864. Epub 2013 Aug 8.
10
Backbone dynamics of an atypical orphan response regulator protein, Helicobacter pylori 1043.非典型孤儿应答调节蛋白幽门螺杆菌1043的主链动力学
Mol Cells. 2013 Feb;35(2):158-65. doi: 10.1007/s10059-013-2303-z. Epub 2013 Feb 21.