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源自腭部的肌上皮瘤病例:肌上皮肿瘤细胞中的胶原生成

Case of myoepithelioma originating from the palate: collagenogenesis in myoepithelial tumor cells.

作者信息

Hara H, Oyama T, Kimura M, Ishii E, Inoue T, Kasai H

机构信息

Pathology Division, Yamanashi Prefectural Central Hospital, Japan.

出版信息

Diagn Cytopathol. 1996 Dec;15(5):415-20. doi: 10.1002/(SICI)1097-0339(199612)15:5<415::AID-DC12>3.0.CO;2-Q.

DOI:10.1002/(SICI)1097-0339(199612)15:5<415::AID-DC12>3.0.CO;2-Q
PMID:8989546
Abstract

We report a case of myoepithelioma of the palate in a 53-yr-old man. Myoepithelioma cells consisting of both plasmacytoid type and spindle type were obtained. A reticular pattern composed of a mosaic arrangement of hyaline-like abundant cytoplasm, and scant matrix and considerable fiber formation were characteristic features of the plasmacytoid type; granular cytoplasm and a snake-like shape were characteristic features of the spindle type. These are important points in differentiating this tumor from cellular type pleomorphic adenoma. The present study shows that tumorous myoepithelial cells can synthesize and secrete extracellular components such as proteoglycans, basal lamina, collagen fibers, and elastic fibers.

摘要

我们报告了一例53岁男性腭部肌上皮瘤的病例。获取了由浆细胞样型和梭形细胞组成的肌上皮瘤细胞。浆细胞样型的特征性表现为:由透明样丰富细胞质的镶嵌排列构成的网状模式、少量基质和大量纤维形成;梭形细胞的特征性表现为颗粒状细胞质和蛇样形态。这些是将该肿瘤与细胞型多形性腺瘤区分开来的要点。本研究表明,肿瘤性肌上皮细胞能够合成和分泌细胞外成分,如蛋白聚糖、基膜、胶原纤维和弹性纤维。

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引用本文的文献

1
Plasmacytoid myoepithelioma of the palate: case report.腭部浆细胞样肌上皮瘤:病例报告
Head Neck Pathol. 2011 Jun;5(2):154-8. doi: 10.1007/s12105-010-0231-1. Epub 2010 Dec 5.