Strobel F H
Emory University Mass Spectrometry Center, Department of Chemistry, Atlanta, Georgia 30322, USA.
Anal Chem. 1997 Jan 1;69(1):105-7. doi: 10.1021/ac9608634.
A method is described to synchronize the scans of the first and second double-focusing mass spectrometers of a tandem double-focusing mass spectrometer. The scans are synchronized by scanning the first mass spectrometer with voltages instead of the magnetic field. The method is demonstrated with scans that provide all of the precursor ions that produce a selected product ion (precursor ion scan). These precursor ion scans are compared to the previous method of obtaining precursor ion scans on a tandem double-focusing mass spectrometer. The precursor ion scans using the synchronized scanning allow for the use of high-energy collisions on any tandem double-focusing mass spectrometer, while limiting the mass range possible in a single scan. The limited mass range may be corrected by obtaining several spectra with different magnetic fields on the first mass spectrometer.
描述了一种用于同步串联双聚焦质谱仪中第一台和第二台双聚焦质谱仪扫描的方法。通过用电压而非磁场扫描第一台质谱仪来实现扫描同步。该方法通过提供产生选定产物离子的所有前体离子的扫描（前体离子扫描）进行了演示。将这些前体离子扫描与在串联双聚焦质谱仪上获得前体离子扫描的先前方法进行了比较。使用同步扫描的前体离子扫描允许在任何串联双聚焦质谱仪上使用高能碰撞，同时限制单次扫描中可能的质量范围。有限的质量范围可通过在第一台质谱仪上用不同磁场获得多个光谱来校正。
