Mastrangelo G, Marzia V, Paruzzolo P, Saia B
Istituto di Medicina del Lavoro, Università di Padova.
G Ital Med Lav. 1995 Jan-Nov;17(1-6):19-21.
The study was conducted to verify a reduction in mortality from tumors in dairy farm workers, exposed to endotoxins, which increase in the host a cytotoxic antitumoral. From the SCAU files of the Province of Padova, we selected 2.415 subjects with informations on: date of hire, date of work termination, number of dairy cattle, area of the farm. The vital status was ascertained through the Communes of residence, and for the 541 decedents the cause of death was established. The standardized mortality ratio (SMR) was calculated on the basis of age-sex-cause-calendar period specific mortality rates in the Veneto. In the 1.641 dairy farm workers, SMRs were significantly low for total tumors (= 81) and lung tumors (= 66), and significantly high for brain tumors (= 283). In other 774 farmers, no significant SMRs were observed. The data will be further processed to verify a dose-response relationship with the occupational risk indicators. Smoking habits will be collected.
开展这项研究是为了验证接触内毒素的奶农肿瘤死亡率是否降低,内毒素可在宿主体内增强细胞毒性抗肿瘤作用。我们从帕多瓦省的SCAU档案中选取了2415名受试者,这些受试者有以下信息:入职日期、工作终止日期、奶牛数量、农场面积。通过居民社区确定生命状态,并确定了541名死者的死因。根据威尼托地区特定年龄、性别、病因和日历时期的死亡率计算标准化死亡率(SMR)。在1641名奶农中,总肿瘤(=81)和肺癌(=66)的SMR显著较低,而脑肿瘤(=283)的SMR显著较高。在其他774名农民中,未观察到显著的SMR。这些数据将进一步处理,以验证与职业风险指标的剂量反应关系。将收集吸烟习惯。