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[不同病程急性支气管炎患者呼出冷凝液的激肽释放酶-激肽指标及生物学成分]

[Kallikrein-kinin indices and biological composition of exhaled condensate in acute bronchitis patients with varying disease course].

作者信息

Goncharova V A, Borisenko L V, Dotsenko E K, Pokhaznikova M A

机构信息

State Scientific Center of Pulmonology, Saint-Petersburg.

出版信息

Klin Med (Mosk). 1996;74(7):46-8.

PMID:8992115
Abstract

Parameters of blood kallikrein-kinin system (KKS) and biochemical composition of humor condensated from the exhaled air have been evaluated in 87 patients with acute bronchitis (36 cases with lingering course and 31 with recurrent). The progression of acute bronchitis is associated with elevated blood concentrations of acute-phase proteins, KKS activation in the blood and high serotonin and lactic acid content in the humor condensated from the exhaled air. Lingering and recurrent course of the disease are characterized by more pronounced reduction in inhibitory activity of kallikrein, in activity of angiotensin-converting enzyme and emergence of noradrenalin in high concentration.

摘要

对87例急性支气管炎患者(36例病程迁延,31例复发)的血液激肽释放酶-激肽系统(KKS)参数及呼出气冷凝液的生化成分进行了评估。急性支气管炎的进展与急性期蛋白血液浓度升高、血液中KKS激活以及呼出气冷凝液中高血清素和乳酸含量有关。疾病的迁延和复发病程的特征是激肽释放酶抑制活性、血管紧张素转换酶活性更明显降低以及高浓度去甲肾上腺素的出现。

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1
[Kallikrein-kinin indices and biological composition of exhaled condensate in acute bronchitis patients with varying disease course].[不同病程急性支气管炎患者呼出冷凝液的激肽释放酶-激肽指标及生物学成分]
Klin Med (Mosk). 1996;74(7):46-8.
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[Changes in the kallikrein-kinin system of patients with erythematous and hemorrhagic forms of erysipelas].
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Kallikrein-kinin system in hepatic experimental models.肝脏实验模型中的激肽释放酶-激肽系统
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Khirurgiia (Mosk). 1999(7):40-2.
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[Selected components of the kallikrein-kinin system and of the renin-angiotensin-aldosterone system in offspring of parents with hypertension].[高血压患者后代中激肽释放酶-激肽系统和肾素-血管紧张素-醛固酮系统的选定成分]
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Cardioprotection and kallikrein-kinin system in acute myocardial ischaemia in mice.小鼠急性心肌缺血中的心脏保护与激肽释放酶-激肽系统
Clin Exp Pharmacol Physiol. 2008 Apr;35(4):489-93. doi: 10.1111/j.1440-1681.2008.04902.x.

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