Goncharova V A, Borisenko L V, Dotsenko E K, Pokhaznikova M A
State Scientific Center of Pulmonology, Saint-Petersburg.
Klin Med (Mosk). 1996;74(7):46-8.
Parameters of blood kallikrein-kinin system (KKS) and biochemical composition of humor condensated from the exhaled air have been evaluated in 87 patients with acute bronchitis (36 cases with lingering course and 31 with recurrent). The progression of acute bronchitis is associated with elevated blood concentrations of acute-phase proteins, KKS activation in the blood and high serotonin and lactic acid content in the humor condensated from the exhaled air. Lingering and recurrent course of the disease are characterized by more pronounced reduction in inhibitory activity of kallikrein, in activity of angiotensin-converting enzyme and emergence of noradrenalin in high concentration.
对87例急性支气管炎患者(36例病程迁延,31例复发)的血液激肽释放酶-激肽系统(KKS)参数及呼出气冷凝液的生化成分进行了评估。急性支气管炎的进展与急性期蛋白血液浓度升高、血液中KKS激活以及呼出气冷凝液中高血清素和乳酸含量有关。疾病的迁延和复发病程的特征是激肽释放酶抑制活性、血管紧张素转换酶活性更明显降低以及高浓度去甲肾上腺素的出现。