Khalmuradov A G, Guliamova T G, Shakirzianova M R, Kerbalaeva A M
Mikrobiologiia. 1996 May-Jun;65(3):345-7.
The activity of the key enzymes of the salvage synthesis and degradation of NAD (nicotinic acid mononucleotide pyrophosphorylase and NAD glycohydrolase) was studied in Saccharomyces cerevisiae mutants selected earlier as potential producers of NAD. An enhanced NAD-producing ability of the mutants was shown to be related to their reduced NAD-degrading activity: thus, NAD glycohydrolase in mutants 110, 118, and 206 was inactive in all growth phases regardless of the level of NAD biosynthesis.
在先前被选为NAD潜在生产者的酿酒酵母突变体中，研究了NAD补救合成和降解的关键酶（烟酸单核苷酸焦磷酸化酶和NAD糖水解酶）的活性。结果表明，突变体增强的NAD生产能力与其降低的NAD降解活性有关：因此，突变体110、118和206中的NAD糖水解酶在所有生长阶段均无活性，无论NAD生物合成水平如何。
