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[不依从性和缺乏长效治疗指征作为排除充分预防复发的原因]

[Non-compliance and lack of indications for depot treatment as reasons for exclusion from adequate prevention of recurrence].

作者信息

Jakobitsch A, Haug H J, Greger J, Osterheide M, Pach J, Sprenger R, Tegeler J, Budde G

机构信息

Psychiatrische Universitätsklinik Basel.

出版信息

Psychiatr Prax. 1996 Sep;23(5):236-9.

PMID:8992517
Abstract

OBJECTIVE

The paper reports on the recruitment of a multicenter study on ambulant prophylactic treatment of schizophrenic disorders.

METHODS

For a study of the relapse-preventative effect of different dose patterns of Flupentixol, a screening phase was carried out among of 1129 schizophrenic patients. The aim of the screening phase was to establish the criteria for exclusion or inclusion in the treatment phase of the study.

RESULTS

Only 62 patients could be included. The reason for 54 patients not being included was a lack of compliance from either the patient or the clinician. The meaning of patient- and therapist-compliance in carrying out a multicenter study is also discussed.

摘要

目的

本文报告一项关于精神分裂症门诊预防性治疗的多中心研究的招募情况。

方法

为研究氟哌噻吨不同剂量模式的预防复发效果，对1129名精神分裂症患者进行了筛选阶段的研究。筛选阶段的目的是确定研究治疗阶段的排除或纳入标准。

结果

仅62名患者可被纳入。54名患者未被纳入的原因是患者或临床医生缺乏依从性。还讨论了患者和治疗师依从性在开展多中心研究中的意义。

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