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[乳腺癌:最新进展]

[Breast carcinoma: state of the art].

作者信息

Pestalozzi B C

机构信息

Departement für Innere Medizin, Universitätsspital Zürich.

出版信息

Schweiz Med Wochenschr. 1996 Nov 30;126(48):2049-58.

PMID:8992624
Abstract

Diagnosis and therapy of breast cancer are briefly reviewed for the general internist. He should know what triple diagnosis, breast-conserving surgery, radiotherapy and adjuvant systemic therapy involve. He should know when to perform a screening mammography, what follow-up examinations after breast cancer are indicated and what dangers loom in metastatic breast cancer. He should know of new therapeutic avenues such as bisphosphonates, new aromatase inhibitors, taxanes, and high-dose chemotherapy with stem cell support. Since advances in the treatment of breast cancer have been achieved mostly through randomized studies, a positive attitude toward such studies and a willingness to take part in them are desirable.

摘要

为普通内科医生简要回顾了乳腺癌的诊断和治疗。他应该了解三联诊断、保乳手术、放疗和辅助全身治疗的内容。他应该知道何时进行乳腺钼靶筛查、乳腺癌术后应进行哪些随访检查以及转移性乳腺癌存在哪些风险。他应该了解双膦酸盐、新型芳香化酶抑制剂、紫杉烷类以及有干细胞支持的大剂量化疗等新的治疗途径。由于乳腺癌治疗的进展大多是通过随机研究取得的,因此对这类研究持积极态度并愿意参与其中是很有必要的。

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