Upalakalin J Nalinee, Collins Laura C, Tawa Nicholas, Parangi Sareh
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Am J Surg. 2006 Jun;191(6):799-805. doi: 10.1016/j.amjsurg.2005.10.021.
Carcinoid tumors in the breast are rare. Most represent metastases from other primary sites, but commonly are mistaken for primary breast lesions.
A literature search of the English language found 59 cases of carcinoid tumors in the breast, 21 (36%) of which were metastases.
We present an additional 3 cases of carcinoid tumors metastatic to the breast and discuss the clinical, radiologic, and pathologic manifestations.
It is important to differentiate between primary breast carcinoid tumor and metastatic disease to the breast because of differences in treatment. All palpable breast masses and mammographically detected lesions should undergo a biopsy examination. In those patients with a known history of carcinoid tumor, pertinent clinical history, and previous surgical specimens should be reviewed to avoid an unnecessary mastectomy. If there is no history of a prior carcinoid tumor, a thorough work-up to look for an occult primary tumor elsewhere should be performed.
乳腺类癌肿瘤罕见。多数为其他原发部位的转移瘤,但常被误诊为原发性乳腺病变。
检索英文文献发现59例乳腺类癌肿瘤病例,其中21例(36%)为转移瘤。
我们另外报告3例转移至乳腺的类癌肿瘤病例,并讨论其临床、放射学及病理学表现。
由于治疗方法不同,区分原发性乳腺类癌肿瘤与乳腺转移瘤很重要。所有可触及的乳腺肿块及乳腺钼靶检查发现的病变均应接受活检。对于有类癌肿瘤已知病史的患者,应查阅相关临床病史及既往手术标本,以避免不必要的乳房切除术。如果没有既往类癌肿瘤病史,则应进行全面检查以寻找其他部位隐匿的原发肿瘤。