Lebech M, Hansen M, Knudsen A
Gynaekologisk-obstetrisk afdeling, Hjørring/Brønderslev Sygehus.
Ugeskr Laeger. 1996 Nov 18;158(47):6778-80.
A series of 180 pregnant women with normal pregnancies participated in the study. A questionnaire concerning the presence of headache, fatigue and oedema of the lower limbs was filled out daily from the 30th gestational week to delivery. After the study period 120 questionnaires, of whom eight were excluded, were available for analysis. The weekly prevalences of headache and fatigue during the observation-period were nearly constant with values of 20% and 50%, respectively. The weekly prevalence of oedema increased significantly from 20% in the 31st week to 60% in the 42nd gestational week. Thirty-five percent had not suffered from headache, 22% did not report fatigue, and 42% did not describe oedema at all during the third trimester. The prevalence of headache and fatigue correlated significantly to increasing parity whereas headache was significantly correlated to decreasing age. Headache, fatigue, and oedema are common symptoms in the third trimester of normal pregnancy, and as such their presence alone should not usually give cause for suspicion of disease.
180名正常妊娠的孕妇参与了该研究。从妊娠第30周开始至分娩，每天填写一份关于是否存在头痛、疲劳和下肢水肿的问卷。研究期结束后，有120份问卷可供分析，其中8份被排除。观察期内头痛和疲劳的每周患病率几乎保持不变，分别为20%和50%。水肿的每周患病率从第31周的20%显著增加到妊娠第42周的60%。在孕晚期，35%的孕妇未出现头痛，22%未报告疲劳，42%根本未描述有水肿。头痛和疲劳的患病率与产次增加显著相关，而头痛与年龄降低显著相关。头痛、疲劳和水肿是正常妊娠晚期的常见症状，因此仅这些症状通常不应引起对疾病的怀疑。
