Knudsen A, Lebech M, Hansen M
Department of Obstetrics and Gynaecology, Hjørring Hospital, Denmark.
Eur J Obstet Gynecol Reprod Biol. 1995 May;60(1):29-33. doi: 10.1016/0028-2243(95)02069-1.
To report on the prevalence of well-being, heartburn, nausea, and vomiting related to gestational week, parity, and age in the third trimester of the normal pregnancy.
Self-administered questionnaire filled in daily by 180 women from 31st gestational week to delivery.
The study was completed by 120 women. The weekly prevalence of well-being decreased from 50% at the 31st gestational week to 24% at the 42nd gestational week (P = 0.00001). The weekly prevalence of heart-burn (approximately 60%), nausea (approximately 16%) and vomiting (approximately 7%) was nearly constant throughout the study period. Well-being was inversely related to parity, (P = 0.006), heartburn positively related to age (P = 0.016), and nausea and vomiting inversely related to age (P = 0.003 and P = 0.044).
Discomforts are customary in the third trimester of normal pregnancy. However, heartburn and especially nausea and vomiting appeared occasionally and were not present for longer periods. The findings that heartburn, nausea and vomiting had different relations to age may suggest different etiologies.
报告正常妊娠晚期幸福感、烧心、恶心和呕吐与孕周、产次及年龄的相关性。
180名女性从妊娠第31周开始至分娩每日自行填写问卷。
120名女性完成了该研究。幸福感的每周患病率从妊娠第31周时的50%降至第42周时的24%（P = 0.00001）。在整个研究期间，烧心的每周患病率（约60%）、恶心（约16%）和呕吐（约7%）几乎保持不变。幸福感与产次呈负相关（P = 0.006），烧心与年龄呈正相关（P = 0.016），恶心和呕吐与年龄呈负相关（P = 0.003和P = 0.044）。
正常妊娠晚期出现不适很常见。然而，烧心尤其是恶心和呕吐偶尔出现，且持续时间不长。烧心、恶心和呕吐与年龄存在不同关系这一发现可能提示不同的病因。
