Mees C, Mecke H, Riedel H H
Abteilung Frauenheilkunde, Christian-Albrechts-Universität Kiel.
Zentralbl Gynakol. 1996;118(9):508-14.
This study compares the incidence of adhesions after using the Endocoagulator by Semm with the incidence of adhesions after using the Nd-YAG-laser with 30 watts and 100 watts. At a total of 100 female Wistar-rats both, the uterine-horns and 2 correspondent spots at the ventral abdominal-walls were coagulatet. resp. vaporized. After 14 resp. 28 days a relaparotomie was made: 1. With the Nd-YAG-laser (30 and 100 watts) (significant) adhesions were found, at the uterine-horns in 100% of all cases with the Endokoagulator in 50%. At the peritoneal spots with the Nd-YAG-laser (30 and 100 watts) (not significant) adhesions were found in 10% of all cases, with the Endokoagulator 5% were found. 2. In addition to the macroscopic results histologic researches were also made: It was shown, that the treatment with Nd-YAG-laser develops a high grade of carbonisation-waste, which is known to be a main cause for the development of adhesions. 3. The division in 14- and 28-day-groups showed no significant differences in the incidence of adhesions. 4. There were found more significant adhesions at the uterine-horns than at the peritoneal-spots.
本研究比较了使用Semm内凝器后粘连的发生率与使用30瓦和100瓦钕钇铝石榴石激光后粘连的发生率。对总共100只雌性Wistar大鼠的子宫角和腹前壁的2个相应部位进行了凝固,分别进行了汽化。在14天和28天后进行再次剖腹手术:1. 使用钕钇铝石榴石激光(30瓦和100瓦)(发现有)明显粘连,在子宫角处,所有病例中有100%出现粘连,使用内凝器的病例中有50%出现粘连。在腹膜部位,使用钕钇铝石榴石激光(30瓦和100瓦)(无明显)粘连在所有病例中的发生率为10%,使用内凝器的发生率为5%。2. 除了宏观结果外,还进行了组织学研究:结果表明,用钕钇铝石榴石激光治疗会产生大量碳化废物,这是已知的粘连形成的主要原因。3. 分为14天组和28天组,粘连发生率无显著差异。4. 在子宫角发现的粘连比在腹膜部位更明显。