Wong K T, Koh K B, Lee S H, Chee C P
Department of Pathology University Hospital, Kuala Lumpur, Malaysia.
Singapore Med J. 1996 Aug;37(4):441-2.
Primary germinomas of the central nervous system carry a good prognosis because of their radiosensitivity. Recurrences are rare and extraneural metastases are even more unusual. One of the possible routes of extraneural spread is via ventriculo-peritoneal shunts which may be required to reduce intracranial pressure. One such case of germinoma metastasizing via a ventriculo-peritoneal shunt is reported. Patients with intracranial germinomas and ventriculo-peritoneal shunts should have close surveillance of their abdomens and may require systemic chemotherapy.
中枢神经系统原发性生殖细胞瘤因其对放疗敏感,预后良好。复发罕见,神经外转移更为少见。神经外扩散的可能途径之一是通过脑室-腹腔分流术,这可能是降低颅内压所需的。本文报告了一例通过脑室-腹腔分流发生转移的生殖细胞瘤病例。患有颅内生殖细胞瘤和脑室-腹腔分流术的患者应密切监测腹部,可能需要全身化疗。