Völkner E, Bartel M, Mohorn M, Leonhardt R, Schaefer R, Rupprecht H
Zentralbl Chir. 1977;102(10):592-7.
After lobectomy a slight increase of pulmonary arterial pressure can already be observed in the state of rest. The resistance of the pulmonary vessels reveals a marked dependance on the date of operation, it increases moderately on strain, but more significantly in the state of rest. At the same time cardiac output is decreased due to the exhaustion of the myocard after straining. Cardiac insufficiency developing postoperatively is due to the reduction of pulmonary hypertension. The reduction of VC and a slight increase of resistance do not cause the arterial PO2 pressure to be lowered under conditions of strain or rest.
肺叶切除术后,即使在静息状态下也可观察到肺动脉压略有升高。肺血管阻力明显取决于手术日期,在运动时适度增加,但在静息状态下增加更为显著。同时,由于运动后心肌耗竭,心输出量减少。术后发生的心功能不全是由于肺动脉高压降低所致。肺活量的降低和阻力的轻微增加并不会导致在运动或静息状态下动脉血氧分压降低。