Purcaro A, Di Luzio V
G Ital Cardiol. 1975;5(3):431-7.
The clinical, laboratory, haemodynamic, cardioangiographic and anatomo-pathological features are described in two patients in whom the association of "Primary Pulmonary Hypertension and Arterial Essential Systemic Hypertension" was noticed. On the basis of a hyperactive neurohormonal mechanism, a hypothetical, ethiological relationship between the pure hypertensive state of both the circulations is discussed. The occurrence of hypertensive systemic episodes and Raynard's phenomena lend weight to the hypothesis that neurohormonal mechanisms might participate in the pathophysiology of this syndrome.
本文描述了两名患者的临床、实验室、血流动力学、心血管造影及解剖病理学特征，这两名患者均被发现患有“原发性肺动脉高压与原发性系统性动脉高血压”。基于神经激素机制的过度活跃，本文探讨了两种循环系统单纯高血压状态之间可能存在的病因学关系。高血压全身性发作和雷诺现象的出现支持了神经激素机制可能参与该综合征病理生理学的假说。
