Staib F, Abel T, Grosse G, Engelbert B
Zentralbl Bakteriol Orig A. 1977 May;238(1):97-117.
In connection with microbiological findings in two patients, a report on septicemia caused by C. tropicalis is given. C. tropicalis is second in frequency to C. albicans in man. Because for the different biological properties of Candida species in each case of isolation of such fungi from clinical specimens an identification of the species is obligatory, because the generalizing diagnosis of "Candida mycosis" may be insufficient for the detection of epidemiological and pathogenetic associations. The possible primary resistance of C. tropicalis against the antimycotic 5-Fluorocytosine (Ancotil) is discussed. It is shown that the antigen similarity within the most important Candida species as e.g. between C. albicans and C. tropicalis may cause a false interpretation of serological results concerning the causative agent of the infection. For a safe inactivation of C. tropicalis on human skin, cleaning with 70% isopropyl alcohol for ten seconds is proposed. Because C. tropicalis is entering the human body preferably through food it is discussed whether a microbiological control of food for patients predisposed for such infections should be performed.
结合两名患者的微生物学检查结果,给出了一份关于热带念珠菌引起败血症的报告。在人类中,热带念珠菌的感染频率仅次于白色念珠菌。由于从临床标本中分离出此类真菌的每种情况下,念珠菌属具有不同的生物学特性,因此必须对菌种进行鉴定,因为“念珠菌病”的笼统诊断可能不足以发现流行病学和发病机制方面的关联。文中讨论了热带念珠菌对抗真菌药物5-氟胞嘧啶(安可替)可能存在的原发性耐药性。结果表明,最重要的念珠菌属内的抗原相似性,如白色念珠菌和热带念珠菌之间的抗原相似性,可能会导致对感染病原体血清学检测结果的错误解读。为了确保在人体皮肤上安全灭活热带念珠菌,建议用70%异丙醇清洗10秒。由于热带念珠菌主要通过食物进入人体,文中讨论了是否应对易感染此类疾病的患者的食物进行微生物控制。