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可透析淋巴细胞提取物(DLyE)治疗儿童期起病的自闭症:一项初步研究。

Dialysable lymphocyte extract (DLyE) in infantile onset autism: a pilot study.

作者信息

Fudenberg H H

机构信息

Neurolmmuno Therapeutics Research Foundation Spartanburg, S.C., USA.

出版信息

Biotherapy. 1996;9(1-3):143-7. doi: 10.1007/BF02628672.

DOI:10.1007/BF02628672
PMID:8993773
Abstract

40 infantile autistic patients were studied. They ranged from 6 years to 15 years of age at entry. 22 were cases of classical infantile autism; whereas 18 lacked one or more clinical defects associated with infantile autism ("pseudo-autism"). Of the 22 with classic autism, 21 responded to transfer factor (TF) treatment by gaining at least 2 points in symptoms severity score average (SSSA); and 10 became normal in that they were main-streamed in school and clinical characteristics were fully normalized. Of the 18 remaining, 4 responded to TF, some to other therapies. After cessation of TF therapy, 5 in the autistic group and 3 of the pseudo-autistic group regressed, but they did not drop as low as baseline levels.

摘要

对40名患自闭症的儿童进行了研究。他们入院时的年龄在6岁至15岁之间。其中22例为典型的儿童自闭症;而另外18例则缺少一项或多项与儿童自闭症相关的临床缺陷(“假性自闭症”)。在22例典型自闭症患者中,21例对转移因子(TF)治疗有反应,症状严重程度评分平均值(SSSA)至少提高了2分;10例恢复正常,能够进入主流学校学习,临床特征也完全恢复正常。在其余18例中,4例对TF有反应,还有一些对其他疗法有反应。停用TF治疗后,自闭症组中有5例、假性自闭症组中有3例病情出现反复,但未降至基线水平。

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