Akansel G, Liu Y, Chitambar C R, Kitapci M T, Akansel S, Krasnow A Z, Isitman A T, Collier B D
Department of Radiology, Medical College of Wisconsin, Milwaukee 53226, USA.
Clin Nucl Med. 1997 Jan;22(1):21-4. doi: 10.1097/00003072-199701000-00005.
Ga-67 and abdominal CT scans of a 72-year-old woman who had malignant lymphoma before, during, and after gallium nitrate/hydroxyurea combination therapy are presented. Disappearance of Ga-67 uptake by the tumor during this treatment despite continuing CT evidence of disease and reappearance of Ga-67 scan abnormalities after cessation of therapy suggests that caution should be exercised when interpreting results of Ga-67 scintigraphy for the detection of tumor viability during gallium nitrate/hydroxyurea therapy.
本文展示了一名72岁女性在接受硝酸镓/羟基脲联合治疗前、治疗期间及治疗后的镓-67扫描和腹部CT扫描结果。尽管CT持续显示有病变,但在该治疗过程中肿瘤对镓-67的摄取消失,且治疗停止后镓-67扫描异常再次出现,这表明在解释硝酸镓/羟基脲治疗期间镓-67闪烁显像检测肿瘤活性的结果时应谨慎。